Molecular BiologybioRxivPreprint
Y chromosome shredding in Anopheles gambiae: insight into the cellular dynamics of a novel synthetic sex ratio distorter.
Matteo Vitale, Nace Kranjc, Jessica Leigh…·Federica Bernardini
This study uses CRISPR/Cas9 to target the Y chromosome in Anopheles gambiae, causing meiotic defects and a female-biased progeny, providing insights into synthetic sex ratio distortion mechanisms.