ImmunologybioRxivPreprint
Uncovering structural determinants of peptide recognition by public and private T-cell receptors
Caner Akıl, Yanchun Peng, Julia McCarthy…·Peijun Zhang
The paper identifies structural differences in TCR recognition of the same pMHC ligand using cryo-EM, showing how similar β chains can pair with different α chains to produce distinct recognition modes.
DOI 10.1101/2025.11.23.690020