Increased expression of developmental Nav1.3 promotes hippocampal CA3 hyperexcitability in early-stage 5xFAD mice
Jiabin Tang, Cameron Swope, Kishan Patel…·Jimcy Platholi
This study shows increased Nav1.3 expression in early-stage 5xFAD mice leads to CA3 hyperexcitability, suggesting Nav1.3 as a target for AD intervention.