MicrobiologyVirusesPeer-reviewed
Differential outcomes of infection by wild-type SARS-CoV-2 and the B.1.617.2 and B.1.1.529 variants of concern in K18-hACE2 transgenic mice
Y. Yicheng He, Jill E. Henley, Philip Sell, Lucio Comai
This study compares the infectivity and inflammatory responses of SARS-CoV-2 wild-type, Delta, and Omicron variants in K18-hACE2 mice, finding differential viral RNA levels and inflammatory marker expression in lung, brain, and olfactory bulb tissues.
4 citations