Jing Wu

Characterization of bronchiolitis and vaccine-induced enhanced respiratory disease in Syrian hamsters caused by respiratory syncytial virus infection

This study characterizes RSV infection and vaccine-induced ERD in Syrian hamsters, showing age-dependent viral replication, pathological changes, and ERD responses similar to humans.

Band-selective IR PRESS for brain tumor spectroscopy allows robust detection of lactate

This paper introduces SPIR-PRESS, a magnetic resonance spectroscopy method that improves lactate detection in brain tumors by reducing lipid interference, showing increased sensitivity and broader metabolite profiling.

ISG15 orchestrates dynamic crosstalk between mitochondrial fat oxidation and type 1 interferon in myeloid cells

This paper identifies a biphasic regulatory loop where type 1 interferon initially enhances mitochondrial fatty acid oxidation (FAO) to amplify its own production, but excessive IFN signaling induces ISG15-mediated inhibition of FAO, creating a negative feedback loop to control inflammation.

Bacteria-mimetic bioadhesives with multivalent mucoadhesion and drug-compatible delivery

This paper develops a bacteria-mimetic bioadhesive using a Vibrio cholerae-derived peptide to achieve strong, non-covalent mucus adhesion and drug delivery.

Multi-omics analysis of the mechanism of alfalfa and wheat-induced rumen flatulence in Xizang sheep

This study investigates the mechanisms of alfalfa and wheat-induced rumen flatulence in Xizang sheep by analyzing microbial, metabolic, and transcriptomic changes.

Adaptation to chronic ER stress enforces pancreatic β-cell plasticity

This study shows chronic ER stress induces β-cell plasticity, but excessive stress leads to identity loss and is linked to T1D progression.