Developmental BiologybioRxivPreprint
An activating mutation in Pdgfrb causes skeletal stem cell defects with osteopenia andovergrowth in mice
Hae Ryong Kwon, Jang Hwan Kim, John P. Woods, Lorin E. Olson
This study shows that a PDGFRβ mutation causes skeletal stem cell defects leading to osteopenia and overgrowth in mice by altering osteogenic and chondrogenic pathways.
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