Measuring the Landscape of CpG Methylation of Individual Repetitive Elements
Yuta Suzuki, Jonas Korlach, Stephen W. Turner, Tatsuya Tsukahara, Junko Taniguchi, Hideaki Yurino, Wei Qu, Jun Yoshimura, Yuji Takahashi, Jun Mitsui, Shoji Tsuji, Hiroyuki Takeda, Shinichi Morishita
The paper develops an algorithm to measure CpG methylation in repetitive elements using SMRT sequencing, achieving high sensitivity and precision in medaka and human genomes.
bioRxiv · Sep 14, 2015Genomics