Author

Jonathan P Mackenzie

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:statistical model· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Alfonso Martinez Arias· 2 shared Pau RuéiD· 2 shared Christian Schröter· 1 shared David Andrew Turner· 1 shared Eleanor Davies· 1 shared

Activity by Year

2014-2015 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 8 mutual co-author links

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2 shared papersDevelopmental Biology

Alfonso Martinez Arias

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2 papers

Recent·Most cited

Developmental BiologyDevelopmentPeer-reviewedJan 1, 2015

FGF/MAPK signaling sets the switching threshold of a bistable circuit controlling cell fate decisions in ES cells

Christian Schröter, Pau Rué, Jonathan P Mackenzie, Alfonso Martinez Arias

The paper identifies FGF/MAPK signaling's role in setting the threshold for a bistable circuit that controls cell fate decisions between epiblast and primitive endoderm in ES cells.

DOI 10.1242/dev.127530

mousestatistical model

𝕏 PostBluesky

Developmental BiologyBMC BiologyPeer-reviewedAug 13, 2014

Brachyury cooperates with Wnt/β-Catenin signalling to elicit Primitive Streak like behaviour in differentiating mouse ES cells.

David Andrew Turner, Pau Rué, Jonathan P Mackenzie…·Alfonso Martinez Arias

This study shows that Brachyury and Wnt/β-Catenin signaling work together to drive primitive streak-like behavior in differentiating mouse ES cells through EMT and cell motility.

DOI 10.1186/s12915-014-0063-7

mousebulk RNA-seq

𝕏 PostBluesky