Cell BiologybioRxivPreprint
Elevations in plasma proinsulin predict the development of diabetes in NOD mice
Vriti Bhagat, Jorden Gill, Mélanie Lopes, C. Bruce Verchere
This study shows that elevated plasma proinsulin and PI:C ratios predict diabetes onset in NOD mice and correlate with reduced beta cell Pc1/3 expression.
DOI 10.1101/2025.07.07.663576