Pharmacology & ToxicologybioRxivPreprint
High-Throughput Morphological Profiling of Patient-Derived Human Liver Organoids for Hepatotoxicity Hazard Identification and Compound Prioritization
Sophia R. Meyer, Max A. Garcia, Neil Zhao…·Jonathan Z. Sexton
This paper uses patient-derived liver organoids and machine learning to identify hepatotoxic compounds by analyzing morphological changes, achieving high accuracy in distinguishing toxicants from non-toxicants.