Author

Juan Du

Yangzhou University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Developmental Biology· 2 Bioengineering· 1 Biophysics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Chikai ZhouiD· 2 shared Jiangwei LiniD· 2 shared Mei Hu· 2 shared Muhammad Ameen JamaliD· 2 shared Shu Wei· 2 shared Wandong BaoiD· 2 shared Yanyan Zhang· 2 shared Aldons J. Lusis· 1 shared

Activity by Year

2016-2026 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersDevelopmental Biology

Chikai ZhouORCID

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Author profile →

5 papers

Recent·Most cited

CryoFAST: A Fab-Aided Cryo-EM Workflow for High-Resolution Structure Determination of Sub-50-kDa Protein Targets

Xiaorun Li, Sean Deng, Weihua Li, Yue Qian, Yawen Li, Juan Du, Le Li, Dongming Qian

CryoFAST improves cryo-EM structure determination for small proteins by combining Fab discovery and computational methods to stabilize targets and enhance resolution.

bioRxiv · Oct 9, 2026 · PreprintBiophysics

A Selective Multivalent NET-Associated Chromatin Neutralizer Resolves Infection-Associated Inflammation in Severe Sepsis

Chuanxu Cheng, Quanxin Ning, Juan Du, Jianati Dawulieti, Chipeng Guo, Madi Sun, Kunbao Zhang, Haijun Li, Qunjie Bi, Jian Li, Zhen Wu, Hanyao Huang, Zhi‐Liang Ji, Jin‐Zhi Du, C Chia-Kai Yang, , Kam W. Leong

This paper develops a multivalent NET-neutralizer that reduces inflammation in severe sepsis by targeting DNA-histone chromatin complexes while maintaining antibacterial activity.

bioRxiv · Jun 30, 2026 · PreprintBioengineering

Generation of Genetically Identical Mammalian Oocytes from Parthenogenetic Double-Haploid Embryonic Stem Cells

Guowei Zou, Shu Wei, Yanyan Zhang, Dingrui Guo, Shuaipeng Li, Mei Hu, Juan Du, Wanchu Wang, Muhammad Ameen Jamal, Wandong Bao, Chikai Zhou, Xiaomin Kang, Shuhui Bian, Jiangwei Lin

This study generates genetically identical mammalian oocytes using parthenogenetic double-haploid embryonic stem cells and blastocyst complementation, producing viable and fertile mice with epigenetic defects.

bioRxiv · Apr 7, 2026 · PreprintDevelopmental Biology

Efficient Reprogramming of the Epiblast Enables the Generation of Cloned Mice

Guomeng Li, Wandong Bao, Mei Hu, Heng Xie, Lianwei Li, Jianlin Xu, Shu Wei, Yue Teng, Yanyan Zhang, Yunan Chen, Lin Ran, Jiawen Liu, Juan Du, Muhammad Ameen Jamal, Zhanshan (Sam) Ma, , Jiangwei Lin

The paper shows that efficient reprogramming in SCNT occurs exclusively in the epiblast, enabling cloned mouse generation through a lineage-specific mechanism.

bioRxiv · Mar 14, 2026 · PreprintDevelopmental Biology

Chromatin variation associated with liver metabolism is mediated by transposable elements

Juan Du, Amy Leung, Candi Trac, Brian W. Parks, Aldons J. Lusis, Rama Natarajan, Dustin E. Schones

The paper identifies transposable elements (TEs) as contributors to chromatin accessibility variation in mice liver, linking TE polymorphism and DNA methylation to metabolic pathway differences.

bioRxiv · May 10, 2016Genomics