Cancer BiologyNature CommunicationsPeer-reviewed
Acetyl transferase EP300 deficiency leads to chronic replication stress mediated by defective fork protection at stalled replication forks
Angelica Barreto-Galvez, Mrunmai Niljikar, Julia Elizabeth Gagliardi…·Advaitha Madireddy
This paper shows that EP300 deficiency causes chronic replication stress and genomic instability in ATLL cells by impairing fork protection and leading to DNA damage and mitotic defects.
4 citations