Author

Julia Meredith

Memorial Sloan Kettering Cancer Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:benchmark study· 1 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Assay:organoid / primary culture· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Neal X. RoseniD· 2 shared Ahmed Mahmoud· 1 shared Alison M. SchramiD· 1 shared Andrea CercekiD· 1 shared Arvin C. DariD· 1 shared Britta WeigeltiD· 1 shared Canan FıratiD· 1 shared Christine Sukhwa· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

Neal X. RosenORCID

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2 papers

Recent·Most cited

Coexistent PTEN and PIK3CA alterations hyperactivate mTORC1 signaling in endometrial cancers and cause their selective sensitivity to mTORC1 inhibition

Hilla Solomon, Radha Mukherjee, Yu Chi Yang, Julia Meredith, Alison M. Schram, Sang Ah Yi, Xiaoping Chen, Michael Tribuzio, Harika Gundlapalli, Justin Meyerowitz, Elisa de Stanchina, Britta Weigelt, Heeseon An, Simon T. Barry, Jacqueline A.M. Smith, , Neal X. Rosen

This study shows that coexisting PTEN and PIK3CA mutations in endometrial cancers hyperactivate mTORC1, making them sensitive to mTORC1 inhibitors but not PI3K or AKT inhibitors.

bioRxiv · Feb 14, 2026 · PreprintCancer Biology

Paired primary-metastasis patient-derived organoids and mouse models identify phenotypic evolution and druggable dependencies of peritoneal metastasis from appendiceal cancer

Ahmed Mahmoud, Philip H. Choi, Christine Sukhwa, Jura Pintar, Henry S. Walch, Nan Zhao, Jonathan Bermeo, Sebastian K. Chung, Manisha S. Raghavan, Samhita Bapat, Qingwen Jiang, Georgios Karagkounis, Julia Meredith, Michael Giarrizzo, Canan Fırat, , Karuna Ganesh

The paper develops patient-derived organoids and mouse models of appendiceal cancer to identify phenotypic changes and drug targets in peritoneal metastasis.

bioRxiv · Feb 17, 2025 · PreprintCancer Biology