ImmunologybioRxivPreprint
Identification of protective human monoclonal antibodies using a K18 hACE2 transgenic mouse SARS-CoV-2 challenge model
Bhavesh R. Borate, Paula A. Pino, Amberlee Hicks…·Andrew J. Fiore-Gartland
This study identifies protective human monoclonal antibodies against SARS-CoV-2 using a K18 hACE2 transgenic mouse model, showing that in vivo testing improves accuracy over in vitro assays.
DOI 10.1101/2025.09.13.675985