D-Mannose treats obesity by increasing adipose Treg cells and suppressing gut Firmicutes
Peter Zanvit, Junji Xu, Nancy Guo, Dunfang Zhang, Michaela Procházková, Thierry Gauthier, Daxesh P. Patel, Alexander Cain, Wenwen Jin, Andrew Bynum, Frank J. Gonzalez, Yasmine Belkaid, WanJun Chen
This study shows that D-mannose reduces obesity in mice by enhancing adipose Treg cells and decreasing gut Firmicutes bacteria.
bioRxiv · Aug 18, 2026 · PreprintImmunology