BiochemistryNature CommunicationsPeer-reviewed
Structural Visualization of HECT-type E3 ligase Ufd4 Accepting and Transferring Ubiquitin to Form K29/K48-branched Polyubiquitination
Xiangwei Wu, Huasong Ai, Junxiong Mao…·Man Pan
This study determines the structural mechanism of HECT-type E3 ligase Ufd4 in catalyzing K29/K48-branched polyubiquitination by capturing structural snapshots of Ub transfer cascades.
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