Cancer BiologybioRxiv
mTORC2/AKT/HSF1/HuR Constitute A Feed-Forward Loop Regulating Rictor Expression And Tumor Growth In Glioblastoma
B. Holmes, A. Benavides-Serrato, R. S. Freeman…·J. Gera
This study identifies a feed-forward loop involving mTORC2/AKT/HSF1/HuR that regulates Rictor expression and promotes glioblastoma growth.
DOI 10.1038/onc.2017.360