K. A. Overmyer

This study shows cytoglobin regulates intracellular hydrogen peroxide and redox signals by reducing hyperoxidation of peroxiredoxins and facilitating Hyper7 reduction, independent of heme-based hydrogen peroxide reactions.

The paper identifies Hem25p as a mitochondrial IPP transporter in yeast, essential for CoQ biosynthesis.

The paper presents the structure and functional analysis of a multimeric COQ7:COQ9 complex involved in CoQ biosynthesis, revealing its mechanism for accessing hydrophobic precursors and coordinating CoQ synthesis.

This study identifies a shared neutrophil activation signature between severe COVID-19 and other acute inflammatory conditions, suggesting common therapeutic targets.

This paper explores using urine metabolomics to monitor health in real time through a smartphone app and discusses initial findings from two healthy subjects.

This study shows that Pptc7 is essential for mitochondrial metabolism and biogenesis, as its deletion in mice causes metabolic defects and early death.

This study characterizes the metabolome of modern and historic dental calculus to identify patterns of metabolite persistence and loss over time.