Cell BiologybioRxiv
Contact sites between endoplasmic reticulum sheets and mitochondria regulate mitochondrial DNA replication and segregation
H. S. Ilamathi, S. Benhammouda, A. Lounas…·M. Germain
The paper shows that ER sheet-mitochondria contact sites regulate mtDNA replication and distribution, with DRP1 loss disrupting this interaction and causing mtDNA issues.
DOI 10.1016/j.isci.2023.107180