K. Arikawa

Single Amplified Genome Catalog Reveals the Dynamics of Mobilome and Resistome in the Human Microbiome

The paper presents a dataset of single amplified genomes (SAGs) and metagenome-assembled genomes (MAGs) from the human microbiome, revealing microbial diversity, mobile genetic elements, and antibiotic resistance gene dynamics.

Unique genomic sequences in a novel Mycobacterium avium subsp. hominissuis lineage enable fine scale transmission route tracing during pig movement

This study identifies a novel Mycobacterium avium subsp. hominissuis lineage in pigs that enables transmission route tracing through unique genetic features.

Revealing within-species diversity in uncultured human gut bacteria with single-cell long-read sequencing

This study develops a single-cell long-read sequencing workflow to generate complete bacterial genomes from uncultured human gut bacteria, revealing structural diversity and phage insertions within species.

Identification of two cancer stem cell-like populations in triple-negative breast cancer xenografts

The paper identifies two cancer stem cell-like populations in TNBC xenografts using transcriptomic analysis and confirms their presence in patient data, suggesting potential as biomarkers and implications for drug resistance.

Genome-wide association study reveals putative bacterial risk factors for cavitary Mycobacterium avium complex lung disease

This study identifies bacterial genetic variants associated with cavitary Mycobacterium avium complex lung disease using genome-wide association analysis of clinical isolates.

Genomic features of Mycobacterium avium subsp. hominissuis isolated from pigs in Japan.

The paper analyzes 30 draft genomes of Mycobacterium avium subsp. hominissuis from Japanese pigs to characterize their genomic features and potential virulence.

Recovery of high-quality assembled genomes via metagenome binning guided with single-cell amplified genomes

This paper introduces MetaSAG, a method using single-cell genomes to improve metagenome binning, resulting in higher quality and strain-resolved microbial genomes from complex communities.

Time-lapse single-cell transcriptomics reveals modulation of histone H3 for dormancy breaking

The paper uses time-lapse single-cell transcriptomics to show histone H3 gene expression fluctuation is crucial for breaking dormancy in fission yeast spores.