M. Sato

Coatomer complex I is required for the transport of SARS-CoV-2 progeny virions from the endoplasmic reticulum-Golgi intermediate compartment

This study identifies COPI as essential for SARS-CoV-2 virion transport from the ERGIC, showing that COPB2 depletion inhibits viral replication.

Discovery of anti-SARS-CoV-2 S2 protein antibody CV804 with broad-spectrum reactivity with various beta coronaviruses and analysis of its pharmacological properties in vitro and in vivo

This study identifies an antibody, CV804, that targets the conserved S2 domain of coronaviruses and shows broad cross-reactivity and ADCC activity against SARS-CoV-2 and related viruses.

Selective Translation Orchestrates Key Signaling Pathways in Primed Pluripotency

This study identifies EIF3D as a key regulator of primed pluripotency through selective translational control of signaling pathways and p53 regulators.

Visualization of spatial distribution of hemoglobin with various oxygen saturations in small animals using a photoacoustic imaging scanner with a hemispherical detector array

This study uses photoacoustic imaging to visualize oxygen saturation distribution in mice, showing changes in hemoglobin oxygen saturation in normal and tumor vessels over time.

Cell source-derived variabilities in human juvenile chondrocyte-derived cell sheet cartilage regenerative effects in a nude rat chondral defect implantation model

The paper was withdrawn due to data reallocation, and the authors request it not be cited as a reference.

Intronic TNR-retained ISOPROPYLMALATE ISOMERASE LARGE SUBUNIT1 transcripts impair leaf development in Arabidopsis

The paper shows that expanded intronic TNR repeats in IIL1 cause growth defects in Arabidopsis by increasing intron-retained transcripts and disrupting protein interactions essential for leaf development.

A bispecific antibody NXT007 exerts a hemostatic activity in hemophilia A monkeys enough to keep a non-hemophiliac state

This paper reports a bispecific antibody NXT007 that shows improved hemostatic activity in hemophilia A monkeys, equivalent to FVIII levels, with lower dosing requirements and longer intervals.

SEN1 is responsible for molybdate transport into nodule symbiosomes for nitrogen fixation in Lotus japonicus

The paper identifies SEN1 as a molybdate transporter responsible for exporting molybdate from host plant cytosol to symbiosomes for nitrogen fixation in Lotus japonicus.

Fission yeast Dis1 is an unconventional TOG/XMAP215 that induces microtubule catastrophe to drive chromosome pulling

This study shows that Dis1 in fission yeast promotes microtubule catastrophe at kinetochores to drive chromosome movement during cell division, differing from other TOG/XMAP215 orthologs.

Hydrodynamics shapes self-recruitment in anemonefishes

The paper compares self-recruitment and larval dispersal between a semi-enclosed bay and an open coast, finding that stronger cross-shore currents in the bay reduce local retention and self-recruitment.

Fission yeast Smi1p participates in the synthesis of the primary septum by regulating β-1,3-glucan synthase Bgs1p function

This study identifies Smi1p as a regulator of Bgs1p function during cytokinesis in fission yeast, showing its role in cell wall synthesis and actomyosin ring dynamics.

In vivo label-free observation of tumor-related blood vessels in small animals using a newly designed photoacoustic 3D imaging system

This study demonstrates a photoacoustic 3D imaging system for non-invasive visualization of tumor-related blood vessels in small animals.

Mis6/CENP-I maintains CENP-A nucleosomes against centromeric non-coding transcription during mitosis

This study shows that Mis6/CENP-I prevents loss of CENP-A nucleosomes at centromeres during mitosis by blocking non-coding transcription.

Excretion of triacylglycerol as a matrix lipid facilitating apoplastic accumulation of a lipophilic metabolite shikonin.

The paper investigates how plants secrete lipophilic metabolites like shikonin by excreting triacylglycerol as a matrix lipid, facilitating apoplastic accumulation.

The two-component response regulator OrrA confers dehydration tolerance by regulating anaKa expression in the cyanobacterium Anabaena sp. strain PCC 7120

Total Biosynthesis of Triacsin Featuring an N-hydroxytriazene Pharmacophore

This study identifies the enzymes responsible for biosynthesizing the N-hydroxytriazene pharmacophore in triacsins, revealing two ATP-dependent enzymes involved in consecutive N-N bond formation.

Deep learning generates custom-made logistic regression models for explaining how breast cancer subtypes are classified

The paper develops an explainable deep learning model to generate logistic regression models for breast cancer subtype classification, showing its utility in identifying gene-subtype relationships.

Quantitative assessment of multiple fish species around artificial reefs using environmental DNA metabarcoding

The paper uses environmental DNA metabarcoding to assess fish species distribution around artificial reefs and finds higher eDNA concentrations at reefs compared to surrounding areas.

Tracheal motile cilia in mice require CAMSAP3 for formation of central microtubule pair and coordinated beating

This study shows CAMSAP3 is essential for forming the central microtubule pair in tracheal motile cilia and enabling coordinated beating in mice.

Postharvest properties of ultra-late maturing peach cultivars and their attributions to Melting Flesh (M) locus: Re-evaluation of M locus in association with flesh texture

This study re-evaluates the Melting Flesh (M) locus in peaches by analyzing two ultra-late maturing cultivars, showing that the non-softening trait in one is due to deletion of endoPG genes, while the other has an unidentified M haplotype associated with melting flesh.

Mutually Beneficial Symbiosis Between Human and Gut-Dominant Bacteroides Species Through Bacterial Assimilation of Host Mucosubstances

This study shows Bacteroides species dominate the human gut microbiota by degrading mucosubstances like GAGs and mucin, producing metabolites beneficial to human health.

The histidine phosphotransfer AHP4 plays a negative role in Arabidopsis plant response to drought

This study shows AHP4 negatively regulates Arabidopsis drought response by modulating gene expression related to stress tolerance mechanisms.

Identification of novel mutations contributing to azole tolerance of Aspergillus fumigatus through in vitro exposure to tebuconazole

Three-dimensional reconstructions of the internal structures of haustoria in parasitic Orobanchaceae

Three-dimensional image reconstruction was used to visualize the spatial organization of cell types in the haustoria of parasitic plants with special reference to their interaction with host roots.

GSK3 activity is a cell fate switch that balances the ratio of vascular cell type

The study identifies GSK3 activity as a cell fate switch that regulates the ratio of sieve elements to companion cells in the phloem.

Excessive assimilation of ammonium by plastidic glutamine synthetase is a major cause of ammonium toxicity in Arabidopsis thaliana

This study identifies plastidic glutamine synthetase 2 (GLN2) as the primary cause of ammonium toxicity in Arabidopsis thaliana by inducing shoot acidity.

Time-lapse single-cell transcriptomics reveals modulation of histone H3 for dormancy breaking

The paper uses time-lapse single-cell transcriptomics to show histone H3 gene expression fluctuation is crucial for breaking dormancy in fission yeast spores.

Lateral organ diversification in plants mediated by the ALOG protein family of transcription factors

The paper identifies MpTAW1, an ALOG family protein in Marchantia polymorpha, as a regulator of lateral organ development and meristem maintenance, showing its conserved function in specifying lateral organ identity across plant lineages.

Ferroptosis is programmed by the coordinated regulation of glutathione and iron metabolism by BACH1

This study identifies BACH1 as a regulator of ferroptosis by modulating glutathione and iron metabolism, showing its role in myocardial infarction resistance.

Identifying the Biosynthetic Gene Cluster for Triacsins with an N-hydroxytriazene Moiety

This study identifies the biosynthetic gene cluster for triacsins in Streptomyces aureofaciens and discovers a new producer species.