Author

K. Beland

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

E. Haddad· 4 shared C. Tremblay-Laganiere· 2 shared H. Romero· 2 shared R. Dicaire· 2 shared W. Lemieux· 2 shared A. B. L. Colamartino· 1 shared A. Colamartino· 1 shared A. Finzi· 1 shared

Activity by Year

2019-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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4 shared papersImmunology

E. Haddad

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Molecular basis for antiviral activity of pediatric neutralizing antibodies targeting SARS-CoV-2 Spike receptor binding domain

Y. Chen, J. Prevost, I. Ullah, H. Romero, V. Lisi, W. D. Tolbert, J. R. Grover, S. Ding, S. Y. Gong, G. Beaudoin-Bussieres, R. Gasser, M. Benlarbi, D. Vezina, S. P. Anand, D. Chatterjee, , A. Finzi

This study identifies two potent neutralizing antibodies, EH3 and EH8, from a pediatric patient that cross-neutralize SARS-CoV-2 variants and provide in vivo protection against the Delta VOC.

bioRxiv · Jul 27, 2022 · PreprintMicrobiology

Generation of Functional Human T Cell Development in NOD/SCID/IL2rγnull Humanized Mice Without Using Fetal Tissue: Application as a Model of HIV Infection and Persistence

C. Colas, O. Volodina, K. Beland, T. N. Q. Pham, Y. Li, F. Dallaire, C. Soulard, W. Lemieux, A. Colamartino, C. Tremblay-Laganiere, R. Dicaire, J. Guimond, N. Patey, S. Vobecky, N. Poirier, , E. Haddad

This paper introduces a new humanized mouse model using cord blood-derived CD34+ cells and pediatric thymic tissue that supports functional T cell development and HIV infection and persistence.

bioRxiv · May 30, 2022Immunology

Genome-wide CRISPR Screens Identify Ferroptosis as a Novel Therapeutic Vulnerability in Acute Lymphoblastic Leukemia

M.-E. Lalonde, M. Sasseville, A.-M. Gelinas, J.-S. Milanese, K. Beland, S. Drouin, E. Haddad, R. Marcotte

This study identifies ferroptosis as a therapeutic vulnerability in B-ALL through genome-wide CRISPR screens and validates it in patient-derived samples.

bioRxiv · Feb 1, 2022Cancer Biology

Efficient and robust NK-Cell transduction with Baboon Envelope pseudotyped lentivector: a major tool for immunotherapy

A. B. L. Colamartino, W. Lemieux, P. Bifsha, S. Nicoletti, N. Chakravarti, J. S. Remon, H. Romero, S. Selleri, K. Beland, M. Guiot, C. Tremblay-Laganiere, R. Dicaire, L. Barreiro, D. A. Lee, E. Verhoeyen, E. Haddad

This paper demonstrates that Baboon Envelope pseudotyped lentiviral vectors efficiently transduce NK-cells, enabling CAR expression and specific killing of cancer cell lines.

bioRxiv · May 2, 2019Immunology