K. Bhatt

Controlling pericellular oxygen tension in cell culture reveals distinct breast cancer responses to low oxygen tensions

This study shows that controlling incubator gas phase O2 is insufficient to control pericellular O2 in cell culture, revealing non-monotonic breast cancer responses to low O2.

HIF-stabilizing Biomaterials: from Hypoxia-mimicking to Hypoxia-inducing

This paper reviews strategies for designing biomaterials that simulate or induce hypoxic conditions to stabilize HIF for biomedical applications, particularly in cancer research.

Keratin isoform shifts modulate motility signals during wound healing

The paper shows that keratin isoform shifts during wound healing modulate motility signals by activating myosin motors through isoform-specific interactions with vimentin shuttling kinases.

Hypoxia-inducing cryogels uncover key cancer-immune cell interactions in an oxygen-deficient tumor microenvironment

This paper introduces hypoxia-inducing cryogels (HICs) to model hypoxic tumor microenvironments and identifies key cancer-immune interactions under low oxygen conditions.

Granger-causal inference of the lamellipodial actin regulator hierarchy by live cell imaging without perturbation

This study uses Granger-causal inference on live cell imaging data to reconstruct cause-effect relationships among actin regulators in lamellipodia without perturbation, identifying distinct activation zones and roles.