Structure and dynamics of the chromatin remodeler ALC1 bound to a PARylated nucleosome
L. Bacic, G. Gaullier, A. Sabantsev, L. Lehmann, K. Brackmann, D. Dimakou, M. Halic, G. Hewitt, S. J. Boulton, S. Deindl
This study determines the structure of ALC1 bound to a PARylated nucleosome using cryo-EM, revealing intermediate states and functional roles in nucleosome remodeling.
bioRxiv · Jun 18, 2021Biophysics