BiochemistrybioRxiv
IMPDH polymers accommodate both catalytically active and inactive conformations
S. Anthony, A. L. Burrell, M. C. Johnson…·J. R. Peterson
The paper investigates IMPDH polymerization and finds that polymerized and non-assembled forms have comparable catalytic activity, with substrate and nucleotide availability affecting filament conformation.
DOI 10.1091/mbc.e17-04-0263