Cell BiologyCellPeer-reviewed
Mechano-dependent sorbitol accumulation supports biomolecular condensate
S. Torrino, W. Oldham, A. R. Tejedor…·T. BERTERO
The paper shows matrix stiffening promotes biomolecular condensation via sorbitol, a mechanosensitive metabolite, and demonstrates this in breast cancer.
DOI 10.1016/j.cell.2024.10.048