Author

W. Oldham

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 3 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. A. Tzika· 1 shared A. Bandyopadhaya· 1 shared A. Chakraborty· 1 shared A. R. Tejedor· 1 shared B. A. Maron· 1 shared B. P. O'Hara· 1 shared C. Chauvet· 1 shared C. Guillermier· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperImmunology

A. A. Tzika

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Lactate transport inhibition therapeutically reprograms fibroblast metabolism in experimental pulmonary fibrosis

D. R. Ziehr, F. Li, K. M. Parnell, N. M. Krah, K. J. Leahy, C. Guillermier, J. Varon, R. M. Baron, B. A. Maron, N. J. Philp, L. P. Hariri, E. Y. Kim, M. L. Steinhauser, R. S. Knipe, J. Rutter, W. Oldham

The paper shows that inhibiting lactate transporters MCT1 and MCT4 reduces myofibroblast differentiation and pulmonary fibrosis in vitro and in vivo.

bioRxiv · Apr 25, 2024Cell Biology

The Bacterial Quorum-Sensing Signal 2-Aminoacetophenone Rewires Immune Cell Bioenergetics through the PGC-1α/ERRα Axis to Mediate Tolerance to Infection

A. Chakraborty, A. Bandyopadhaya, V. Singh, F. Kovacic, S. Cha, W. Oldham, A. A. Tzika, L. Rahme

This study shows that the bacterial QS signal 2-AA modulates immune cell bioenergetics via the PGC-1α/ERRα axis, promoting immune tolerance and pathogen persistence.

bioRxiv · Feb 26, 2024Immunology

Mechano-dependent sorbitol accumulation supports biomolecular condensate

S. Torrino, W. Oldham, A. R. Tejedor, I. Sanchez-Burgos, N. Rachedi, K. Fraissard, C. Chauvet, C. Sbai, B. P. O'Hara, S. Abelanet, F. Brau, S. Clavel, R. Collepardo-Guevara, J. Rene Espinosa, I. ben-sahra, T. BERTERO

The paper shows matrix stiffening promotes biomolecular condensation via sorbitol, a mechanosensitive metabolite, and demonstrates this in breast cancer.

bioRxiv · Jul 24, 2023Cell Biology