Author

K. H. Pearce

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. C. Puhl· 2 shared B. L. Hurst· 2 shared B. Yount· 2 shared E. J. Fritch· 2 shared F. Scholle· 2 shared J. A. Levi· 2 shared L. Premkumar· 2 shared N. J. Johnson· 2 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

A. C. Puhl

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintDec 16, 2021

Vandetanib Reduces Inflammatory Cytokines and Ameliorates COVID-19 in Infected Mice

A. C. Puhl, G. F. Gomes, S. Damasceno…·S. Ekins

This study tests FDA-approved kinase inhibitors against SARS-CoV-2 in vitro and in vivo, finding that vandetanib reduces inflammatory cytokines and mitigates lung inflammation in infected mice without reducing viral load.

DOI 10.1101/2021.12.16.472155

mouseexperimental assay

𝕏 PostBluesky

Pharmacology & ToxicologybioRxivDec 1, 2020

Repurposing the Ebola and Marburg Virus Inhibitors Tilorone, Quinacrine and Pyronaridine: In vitro Activity Against SARS-CoV-2 and Potential Mechanisms

A. C. Puhl, E. J. Fritch, T. R. Lane…·S. Ekins

This study evaluates the in vitro antiviral activity of three Ebola and Marburg virus inhibitors against SARS-CoV-2 and explores their potential mechanisms of action.

DOI 10.1021/acsomega.0c05996

humanexperimental assay

𝕏 PostBluesky