Cancer BiologybioRxivPreprint
Longitudinal whole-exome sequencing of cell-free DNA unravels the metastatic evolutionary dynamics of BRCA2 mutated breast cancer
R. K. Hastings, M. R. Openshaw, M. Vazquez…·J. A. Shaw
This study uses longitudinal whole-exome sequencing of cell-free DNA to track the evolutionary dynamics of BRCA2-mutated breast cancer over 12 years, identifying key mutations and immune escape mechanisms.
DOI 10.1101/2020.01.10.901330