C. Richards

Matching dynamically varying forces with multi-motor-unit muscle models: A simulation study

This study simulates how different motor unit pool models affect force generation in muscles during static and dynamic tasks, finding that feedback improves performance, especially for physiologically relevant models.

Evolution of a fatty acyl-CoA elongase underlies desert adaptation in Drosophila

This study identifies a fatty acyl-CoA elongase gene, mElo, as crucial for desiccation resistance in Drosophila mojavensis through evolutionary changes enabling the synthesis of long-chain methylbranched cuticular hydrocarbons.

Desiccation resistance differences in Drosophila species can be largely explained by variations in cuticular hydrocarbons

This study shows that variations in cuticular hydrocarbons, particularly methyl-branched CHCs, largely explain desiccation resistance differences among Drosophila species.

Response to nitrogen and salinity in Rhizophora mangle propagules varies by maternal family and population of origin

This study examines how Rhizophora mangle propagules respond to salt and nitrogen levels, showing population-specific plasticity and survival differences.

Purinoreceptors and ectonucleotidases control ATP-induced calcium waveforms and calcium-dependent responses in microglia

This study uses computational modeling to show that purinoreceptors and ectonucleotidases regulate ATP-induced calcium waveforms and microglia responses, with different waveforms driving distinct functional outcomes.

Species' traits and exposure as a future lens for quantifying seabird bycatch vulnerability in global fisheries

The paper develops a vulnerability framework to classify seabirds bycatch vulnerability using species traits, exposure, and adaptive capacity, revealing patterns and gaps in current assessments.

Bycatch mitigation could prevent strong changes in the ecological strategies of seabird communities across the globe

This study shows that bycatch mitigation could prevent shifts in seabird community traits globally, especially in the North Atlantic and Southern Oceans.

DksA-dependent regulation of RpoS contributes to Borrelia burgdorferi tick-borne transmission and mammalian infectivity

This study shows DksA regulates RpoS-dependent gene expression in B. burgdorferi, essential for tick transmission and mammalian infectivity, through interactions with RNA polymerase and post-transcriptional control of RpoS.

Biological traits of seabirds predict extinction risk and vulnerability to anthropogenic threats

This study identifies seabird traits linked to extinction risk and vulnerability to human threats by analyzing trait space segregation and redundancy across species.

Induction of AmpC-mediated-βlactam resistance requires a single lytic transglycosylase in Agrobacterium tumefaciens

This paper identifies MltB3 as a key enzyme required for AmpC-mediated β-lactam resistance in Agrobacterium tumefaciens, enabling the development of antibiotic-sensitive strains for plant transformation.

Reduced representation characterization of genetic and epigenetic differentiation to oil pollution in the foundation plant Spartina alterniflora

The paper examines genetic and epigenetic differentiation in Spartina alterniflora populations exposed to oil pollution, finding correlations between exposure and variation in DNA methylation, gene expression, and genotype.

Longitudinal whole-exome sequencing of cell-free DNA unravels the metastatic evolutionary dynamics of BRCA2 mutated breast cancer

This study uses longitudinal whole-exome sequencing of cell-free DNA to track the evolutionary dynamics of BRCA2-mutated breast cancer over 12 years, identifying key mutations and immune escape mechanisms.

The Antiviral and Cancer Genomic DNA Deaminase APOBEC3H Is Regulated by a RNA-Mediated Dimerization Mechanism

This study identifies an RNA-mediated dimerization mechanism that regulates APOBEC3H DNA deaminase activity, localization, and antiviral function.