ImmunologybioRxivPreprint
CD40 provides immune privilege to the bone marrow hematopoietic niche
B. Bassani, A. Gulino, P. Portararo…·S. Sangaletti
This study shows that CD40 on bone marrow mesenchymal stem cells (BM-MSCs) promotes immune tolerance and prevents graft-versus-host disease by regulating Treg function and B-cell development.