Author

K. Kirk

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Organism:mouse· 1 Organism:plant (other)· 1 Assay:proteomics· 1

Frequent Co-Authors

E. Rajendran· 3 shared G. G. van Dooren· 3 shared B. Steinhoefel· 2 shared M. Blume· 2 shared M. J. McConville· 2 shared S. Broer· 2 shared S. J. Fairweather· 2 shared A. M. Lehane· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersMicrobiology

E. Rajendran

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Author profile →

4 papers

Recent·Most cited

Generation and characterisation of P. falciparum parasites with a G358S mutation in the PfATP4 Na+ pump and clinically relevant levels of resistance to some PfATP4 inhibitors

D. Qiu, J. V. Pei, J. E. O. Rosling, D. Li, Y. Xue, J. S. Penington, K. Kümpornsin, Y. T. V. Aw, J. Y. H. Aw, H. Hasemer, A. S. M. Dennis, M. C. Ridgway, A. T. Papenfuss, M. C. S. Lee, G. G. van Dooren, , A. M. Lehane

This paper shows that a G358S mutation in PfATP4 confers clinically relevant resistance to cipargamin and (+)-SJ733 in P. falciparum parasites.

bioRxiv · Jan 11, 2022Microbiology

Coordinated Action of Multiple Transporters in the Acquisition of Essential Cationic Amino Acids by the Intracellular Parasite Toxoplasma gondii

S. J. Fairweather, E. Rajendran, M. Blume, K. Javed, B. Steinhoefel, M. J. McConville, K. Kirk, S. Broer, G. G. van Dooren

This study identifies TgApiAT6-1 as a second arginine transporter in Toxoplasma gondii, showing it mediates both lysine and arginine uptake and is essential for parasite proliferation.

bioRxiv · Jun 25, 2021Microbiology

Substrate-mediated regulation of the arginine transporter of Toxoplasma gondii

E. Rajendran, M. Clark, C. Goulart, B. Steinhoefel, E. T. Tjhin, N. C. Smith, K. Kirk, G. G. van Dooren

This study shows that Toxoplasma gondii regulates its arginine transporter TgApiAT1 expression in response to arginine availability, mediated by a uORF in the transcript.

bioRxiv · Oct 9, 2019Microbiology

Characterization of the apicomplexan amino acid transporter (ApiAT) family in Toxoplasma gondii

K. E. R. Parker, S. J. Fairweather, E. Rajendran, M. Blume, M. J. McConville, S. Broer, K. Kirk, G. van Dooren

The paper identifies and characterizes the ApiAT family of amino acid transporters in Toxoplasma gondii, showing their role in amino acid scavenging and parasite virulence.

bioRxiv · Apr 26, 2018Microbiology