D. Qiu

Pools of independently cycling inositol phosphates revealed by pulse labeling with 18O-water

The paper uses 18O-water labeling to study phosphate group dynamics in inositol phosphates across species, revealing distinct pools with different cycling behaviors.

Simultaneous generation of osteoblasts and adipocytes by a bivalent differentiation medium from bone marrow stromal/stem cells (BMSCs)

This paper introduces a bivalent differentiation medium that enables BMSCs to simultaneously generate osteoblasts and adipocytes, with a method to assess lineage commitment using staining techniques.

A 3-component module maintains sepal flatness in Arabidopsis

The paper identifies a 3-component module involving VIP4, ARF3, and VANGUARD1 that maintains sepal flatness in Arabidopsis by regulating cell wall stiffness and growth balance.

Conservation of heat stress acclimation by the inositol polyphosphate multikinase, IPMK responsible for 4/6-InsP7 production in land plants

This study identifies IPMK as the enzyme responsible for producing 4/6-InsP7 in land plants and shows its role in heat stress acclimation through regulation of HSF transcription activity.

The impact of multiband and in-plane acceleration on white matter microstructure analysis

This study evaluates how multiband and in-plane acceleration affect white matter microstructure analysis in older adults with varying cognitive status, finding both benefits and drawbacks in reliability and group differences.

Bacterial Pathogen Infection Triggers Magic Spot Nucleotide Signaling in Arabidopsis thaliana Chloroplasts Through Specific RelA/SpoT Homologs

This study uses CE-MS to measure (p)ppGpp levels in Arabidopsis thaliana during infection, showing increased ppGpp via RSH2/RSH3 and PAMP signaling.

Inositol pyrophosphate dynamics reveals control of the yeast PHO starvation program through 1,5-IP8 and the SPX domain of Pho81

The paper shows that 1,5-IP8 decline triggers the yeast PHO starvation response by inactivating Pho81 through its SPX domain, revealing a unified model of phosphate signaling across eukaryotes.

Vampyroteuthis pseudoinfernalis sp. nov.: the second extant widespread deep sea squid species of Vampyromorpha (Cephalopoda: Coleoidea)

The paper describes a new species of vampire squid, Vampyroteuthis pseudoinfernalis, distinguished by morphological and genetic differences from the known species Vampyroteuthis infernalis.

β-Lapachone Regulates Mammalian Inositol Pyrophosphate Levels in an NQO1- and Oxygen-dependent Manner

This study shows β-lapachone reduces inositol pyrophosphate levels in mammalian cells through NQO1-dependent oxygen activation and ROS production.

Metabolic consequences of polyphosphate synthesis and imminent phosphate limitation

This study investigates how polyphosphate synthesis and phosphate limitation affect yeast metabolism, revealing that polyphosphate serves metabolic roles beyond phosphate storage.

Capillary electrophoresis mass spectrometry identifies new isomers of inositol pyrophosphates in mammalian tissues

This study uses capillary electrophoresis mass spectrometry to identify new isomers of inositol pyrophosphates in mammalian tissues and patient samples.

Stable isotopomers of myo-inositol to uncover the complex MINPP1-dependent inositol phosphate network

The paper uses stable isotopomers of myo-inositol to analyze the MINPP1-dependent inositol phosphate network in human cells, revealing a novel dephosphorylation branch.

Arabidopsis PFA-DSP-type phosphohydrolases target specific inositol pyrophosphate messengers

This study identifies Arabidopsis PFA-DSP proteins as specific inositol pyrophosphate phosphohydrolases, revealing their role in regulating these signaling molecules.

Generation and characterisation of P. falciparum parasites with a G358S mutation in the PfATP4 Na+ pump and clinically relevant levels of resistance to some PfATP4 inhibitors

This paper shows that a G358S mutation in PfATP4 confers clinically relevant resistance to cipargamin and (+)-SJ733 in P. falciparum parasites.

Photoaffinity capture compounds to profile the Magic Spot Nucleotide interactomes

The paper identifies Magic Spot Nucleotide interactomes in E. coli and S. typhimurium using photoaffinity capture compounds, revealing new targets like ApaH.

Analysis of Inositol Phosphate Metabolism by Capillary Electrophoresis Electrospray Ionization Mass Spectrometry (CE-ESI-MS)

This paper develops a CE-ESI-MS method to analyze inositol phosphates and pyrophosphates, revealing unknown synthesis pathways in mammals.