RhoA within myofibers controls satellite cell microenvironment to allow hypertrophic growth
C. Noviello, K. Kobon, L. Delivry, T. Guilbert, F. Julienne, P. Maire, V. Randrianarison-Huetz, A. Sotiropoulos
This study shows RhoA in myofibers promotes hypertrophy by regulating satellite cell fusion through ECM remodeling and macrophage recruitment without affecting protein synthesis.
bioRxiv · Jan 18, 2021Physiology