PhysiologybioRxiv
RhoA within myofibers controls satellite cell microenvironment to allow hypertrophic growth
C. Noviello, K. Kobon, L. Delivry…·A. Sotiropoulos
This study shows RhoA in myofibers promotes hypertrophy by regulating satellite cell fusion through ECM remodeling and macrophage recruitment without affecting protein synthesis.
DOI 10.1016/j.isci.2021.103616