Author

K. Lakovits

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Hladik· 3 shared S. Knapp· 3 shared A.-D. Gorki· 2 shared F. Oberndorfer· 2 shared L. Boon· 2 shared R. Gawish· 2 shared A. Alimohammadi· 1 shared A. Bergthaler· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersImmunology

A. Hladik

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A neutrophil-B-cell axis governs disease tolerance during sepsis via Cxcr4

R. Gawish, B. Maier, G. Obermayer, M. Watzenboeck, A.-D. Gorki, F. Quattrone, A. Farhat, K. Lakovits, A. Hladik, A. Korosec, A. Alimohammadi, I. Mesteri, F. Oberndorfer, F. Oakley, J. Brain, , S. Knapp

This study identifies a neutrophil-B-cell axis that promotes disease tolerance during sepsis through Cxcr4 activation, reducing organ damage and immunothrombosis.

bioRxiv · Mar 21, 2022Immunology

ACE2 is the critical in vivo receptor for SARS-CoV-2 in a novel COVID-19 mouse model with TNF- and IFNγ-driven immunopathology

R. Gawish, P. Starkl, L. Pimenov, A. Hladik, K. Lakovits, F. Oberndorfer, S. J. F. Cronin, A. Ohradanova-Repic, G. Wirnsberger, B. Agerer, L. Endler, T. Capraz, J. W. Perthold, A. Hagelkruys, N. Montserrat, , S. Knapp

This paper develops a mouse-adapted SARS-CoV-2 strain, maVie16, to model COVID-19 in mice, showing that ACE2 is critical for disease and that blocking TNF/IFNγ reduces immunopathology.

bioRxiv · Aug 9, 2021Immunology

Murine ex vivo cultured alveolar macrophages provide a novel tool to study tissue-resident macrophage behavior and function

A.-D. Gorki, D. Symmank, S. Zahalka, K. Lakovits, A. Hladik, B. Langer, B. Maurer, V. Sexl, R. Kain, S. Knapp

This paper introduces a method to culture and expand murine alveolar macrophages ex vivo over several months, showing they retain key features and functions.

bioRxiv · Feb 11, 2021Immunology