Author

K. Lind

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Brewster· 1 shared A. C. Pearce· 1 shared A. Czibere· 1 shared A. Denis· 1 shared A. Di Ruscio· 1 shared A. Dossang· 1 shared A. K. Ebralidze· 1 shared A. M. Jagger· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. Brewster

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Author profile →

2 papers

Recent·Most cited

Development of a small molecule that corrects misfolding and increases secretion of Z α1-antitrypsin

D. Lomas, J. A. Irving, C. Arico-Muendel, S. Belyanskaya, A. Brewster, M. J. B. Brown, C.-w. Chung, H. Dave, A. Denis, N. Dodic, A. Dossang, P. Eddershaw, D. Klimaszewska, I. Haq, D. Holmes, , A. C. Pearce

This study identifies a small molecule that stabilizes Z α1-antitrypsin, reduces polymerization, and increases its secretion in cells and mice.

bioRxiv · Jul 26, 2020Pharmacology & Toxicology

Core binding factor leukemia hijacks T-cell prone PU.1 antisense promoter

E. van der Kouwe, G. Heller, A. Czibere, L. H. Castilla, R. Delwel, A. Di Ruscio, A. K. Ebralidze, M. Forte, L. Kazianka, C. Kornauth, T. Le, K. Lind, I. A. Monteiro Barbosa, A. Pichler, J. A. Pulikkan, , P. B. Staber

The paper shows that CBF fusions in AML activate the PU.1 antisense promoter, reducing sense PU.1 transcription and blocking myeloid differentiation, similar to T-cell differentiation.

bioRxiv · May 29, 2020Cancer Biology