Discovery of prevalent, clinically actionable tumor neoepitopes via integrated biochemical and cell-based platforms
H. Gurung, A. J. Heidersbach, M. Darwish, P. Chan, J. Li, M. Beresini, O. Zill, A. Wallace, A.-J. Tong, D. Hascall, E. Torres, A. Chang, K. Lou, Y. Abdolazimi, U. Uche, , C. M. Rose
The paper identifies 84 clinically relevant neoepitope-HLA pairs from 37 shared cancer neoantigens using a combination of biochemical assays and computational methods.
bioRxiv · Oct 27, 2022 · PreprintCancer Biology