Author

C. Blanchette

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 3 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:drug response / drug discovery· 4 Approach:statistical model· 4 Organism:human· 3 Assay:proteomics· 3 Approach:deep learning· 2 Research Focus:gene regulatory network inference· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

A.-J. Tong· 3 shared C. M. Rose· 3 shared M. Darwish· 3 shared B. Haley· 2 shared L. Delamarre· 2 shared R. Bourgon· 2 shared S. Jhunjhunwala· 2 shared Y. Abdolazimi· 2 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCancer Biology

A.-J. Tong

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

HLApollo: A superior transformer model for pan-allelic peptide-MHC-I presentation prediction, with diverse negative coverage, deconvolution and protein language features.

W. J. Thrift, N. W. Lounsbury, Q. Broadwell, A. Heidersbach, E. Freund, Q. Phung, Y. Abdolazimi, J. Chen, A.-H. Capietto, A.-J. Tong, C. M. Rose, C. Blanchette, J. Lill, B. Haley, L. Delamarre, , S. Jhunjhunwala

HLApollo improves MHC-I peptide presentation prediction with a transformer model, showing better performance than existing methods and offering pan-allelic generalization.

bioRxiv · Dec 8, 2022 · PreprintImmunology

Discovery of prevalent, clinically actionable tumor neoepitopes via integrated biochemical and cell-based platforms

H. Gurung, A. J. Heidersbach, M. Darwish, P. Chan, J. Li, M. Beresini, O. Zill, A. Wallace, A.-J. Tong, D. Hascall, E. Torres, A. Chang, K. Lou, Y. Abdolazimi, U. Uche, , C. M. Rose

The paper identifies 84 clinically relevant neoepitope-HLA pairs from 37 shared cancer neoantigens using a combination of biochemical assays and computational methods.

bioRxiv · Oct 27, 2022 · PreprintCancer Biology

Sensitive and quantitative detection of MHC-I displayed neoepitopes using a semi-automated workflow and TOMAHAQ mass spectrometry

S. B. Pollock, C. M. Rose, M. Darwish, R. Bouziat, L. Delamarre, C. Blanchette, J. R. Lill

The paper develops a semi-automated workflow with TOMAHAQ mass spectrometry to detect and quantify MHC-I displayed neoepitopes in various cell lines.

bioRxiv · Dec 16, 2020Cancer Biology

Transposable Element Expression In Tumors Is Associated With Immune Infiltration And Increased Antigenicity

Y. Kong, C. Rose, A. A. Cass, M. Darwish, S. Lianoglou, P. M. Haverty, A.-J. Tong, C. Blanchette, I. Mellman, R. Bourgon, G. John, S. Jhunjhunwala, M. L. Albert, H. Chen-Harris

The paper shows that transposable element expression in tumors correlates with immune infiltration and increased antigenicity, suggesting potential synergy with immunotherapy.

bioRxiv · Aug 9, 2018Cancer Biology