MicrobiologybioRxiv
Replenishing the malaria drug discovery pipeline: Screening and hit evaluation of the MMV Hit Generation Library 1 (HGL1) against asexual blood stage Plasmodium falciparum, using a nano luciferase reporter read-out
K. J. Dechering, M. Timmerman, K. Rensen…·M. Duffey
The paper screens a compound library against Plasmodium falciparum using a nanoluciferase assay, identifying 33 high-quality hits for antimalarial drug development.
DOI 10.1016/j.slasd.2022.07.002