Cell BiologybioRxiv
Focused ultrasound stimulates ER localized mechanosensitive PANNEXIN-1 to mediate intracellular calcium release in invasive cancer cells
N. S. Lee, C. W. Yoon, Q. Wang…·K. K. Shung
This study shows focused ultrasound activates ER-localized PANX1 in invasive cancer cells, triggering calcium release and cytokine release, suggesting a new adjuvant therapy for cancer immunotherapy.
DOI 10.3389/fcell.2020.00504