PhysiologybioRxiv
Sprouty2 limits intestinal tuft and goblet cell numbers through GSK3β-mediated restriction of epithelial IL-33.
M. A. Schumacher, J. J. Hsieh, C. Y. Liu…·M. R. Frey
This study shows that Sprouty2 restricts intestinal tuft and goblet cell numbers via GSK3β-mediated IL-33 expression, with implications for inflammatory bowel disease.
DOI 10.1038/s41467-021-21113-7