Author

K. Marquardt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Assay:scRNA-seq· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

K. Mowen· 2 shared L. A. Sherman· 2 shared R. C. Orozco· 2 shared A. Domissy· 1 shared I. Pratumchai· 1 shared J. R. Teijaro· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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2 shared papersImmunology

K. Mowen

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintJun 28, 2023

Autoimmunity associated allele of tyrosine phosphatase gene PTPN22 enhances anti-viral immunity

R. C. Orozco, K. Marquardt, I. Pratumchai…·L. A. Sherman

The study shows that the PTPN22 1858C>T allele, linked to autoimmunity, enhances anti-viral immunity by improving CD4 T cell responses and CD8-cDC function during LCMV infection.

DOI 10.1101/2023.06.28.546768

mousescRNA-seq

𝕏 PostBluesky

ImmunologybioRxivMar 17, 2021

Pro-autoimmune allele of tyrosine phosphatase, PTPN22, enhances tumor immunity

R. C. Orozco, K. Marquardt, K. Mowen, L. A. Sherman

This study shows that a pro-autoimmune allele of PTPN22 enhances anti-tumor immunity by increasing immune cell infiltration and reducing immunosuppressive cells in tumors.

DOI 10.4049/jimmunol.2100304

mouseexperimental assay

𝕏 PostBluesky