Computational exploration of the global microbiome for antibiotic discovery
C. D. Santos-Junior, M. D. T. Torres, Y. Duan, A. Rodriguez del Rio, T. S. B. Schmidt, H. Chong, A. Fullam, K. Michael, C. Zhu, A. Houseman, J. Somborski, A. Vines, X.-M. Zhao, P. Bork, J. Huerta-Cepas, , L. P. Coelho
The paper uses machine learning to predict antimicrobial peptides from microbiome data, identifies novel peptides, and validates their antibacterial activity against drug-resistant pathogens.
bioRxiv · Aug 31, 2023Microbiology