Author

H. Chong

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Approach:machine learning (classical)· 1 Assay:metagenomics· 1

Frequent Co-Authors

D. Yu· 2 shared H. Yan· 2 shared Y. He· 2 shared Y. Zhu· 2 shared A. Acab· 1 shared A. Bhattacharya· 1 shared A. Fullam· 1 shared A. Gerasimova· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersMicrobiology

D. Yu

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Computational exploration of the global microbiome for antibiotic discovery

C. D. Santos-Junior, M. D. T. Torres, Y. Duan, A. Rodriguez del Rio, T. S. B. Schmidt, H. Chong, A. Fullam, K. Michael, C. Zhu, A. Houseman, J. Somborski, A. Vines, X.-M. Zhao, P. Bork, J. Huerta-Cepas, , L. P. Coelho

The paper uses machine learning to predict antimicrobial peptides from microbiome data, identifies novel peptides, and validates their antibacterial activity against drug-resistant pathogens.

bioRxiv · Aug 31, 2023Microbiology

A strict requirement in proteasome substrates for spacing between ubiquitin tag and degradation initiation elements

C. Davis, B. L. Spaller, E. Choi, J. B. Kurrasch, H. Chong, S. Elsasser, D. Finley, A. Matouschek

The paper shows that the distance between ubiquitin tags and degradation initiation elements determines proteasome-mediated protein degradation efficiency.

bioRxiv · Aug 8, 2023 · PreprintBiochemistry

Analytical validation and performance characteristics of a 48-gene next-generation sequencing panel for detecting potentially actionable genomic alterations in myeloid neoplasms

S. H. Rosenthal, A. Gerasimova, C. Ma, H.-R. Li, A. Grupe, H. Chong, A. Acab, A. Smolgovsky, R. Owen, C. Elzinga, R. Chen, D. Sugganth, T. Freitas, J. Graham, K. Champion, , F. Lacbawan

The paper validates a 48-gene NGS panel for detecting actionable genomic mutations in myeloid neoplasms, showing high sensitivity and specificity.

bioRxiv · Nov 30, 2020Cancer Biology

Design of potent membrane fusion inhibitors against SARS-CoV-2, an emerging coronavirus with high fusogenic activity

Y. Zhu, D. Yu, H. Yan, H. Chong, Y. He

This study identifies SARS-CoV-2's high fusogenic activity via ACE2 receptor and designs a potent lipopeptide inhibitor, IPB02, targeting the HR2 region of the spike protein.

Journal of Virology · Jul 1, 2020Peer-reviewedMicrobiology

Cross-reactive neutralization of SARS-CoV-2 by serum antibodies from recovered SARS patients and immunized animals

Y. Zhu, D. Yu, Y. Han, H. Yan, H. Chong, L. Ren, J. Wang, T. Li, Y. He

This study shows that antibodies from SARS-CoV survivors and immunized animals neutralize SARS-CoV-2, suggesting potential for broad-spectrum vaccines against emerging coronaviruses.

bioRxiv · Apr 20, 2020Microbiology