The oncogenic Runx3-Myc axis defines p53-deficient osteosarcomagenesis
S. Otani, Y. Date, T. Ueno, T. Ito, S. Kajikawa, K. Omori, I. Taniuchi, M. Umeda, T. Komori, J. Toguchida, K. Ito
This study identifies the Runx3-Myc axis as a driver of p53-deficient osteosarcomagenesis in human and mouse models.
bioRxiv · May 3, 2021 · PreprintCancer Biology