Author

K. Poole

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1

Frequent Co-Authors

D. W. Schmidtke· 1 shared F. Faucher· 1 shared J. Zheng· 1 shared K. S. Iyer· 1 shared M. Petroll· 1 shared N. Neville· 1 shared S. Wang· 1 shared V. D. Varner· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioengineering

D. W. Schmidtke

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2 papers

Recent·Most cited

Corneal keratocytes, fibroblasts, and myofibroblasts exhibit distinct transcriptional profiles in vitro

K. Poole, K. S. Iyer, D. W. Schmidtke, M. Petroll, V. D. Varner

This study identifies distinct transcriptional profiles of cultured corneal keratocytes, fibroblasts, and myofibroblasts, revealing genes and pathways involved in their differentiation and potential therapeutic targets.

bioRxiv · Feb 28, 2024 · PreprintBioengineering

Structure-guided disruption of pseudopilus tip inhibits Type II secretion in Pseudomonas aeruginosa

Z. Jia, Y. Zhang, F. Faucher, W. Zhang, S. Wang, N. Neville, K. Poole, J. Zheng

The paper identifies XcpV and XcpW as essential pseudopilin components of the T2SS tip, develops structure-based inhibitory peptides that disrupt the complex and inhibit T2SS in vivo, reducing P. aeruginosa virulence.

bioRxiv · Apr 17, 2018Microbiology