Author

K. Quast

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

E. Schruf· 2 shared H. Q. Le· 2 shared J. P. Garnett· 2 shared M. J. Thomas· 2 shared M. Schuler· 2 shared V. Schroeder· 2 shared A. Warth· 1 shared B. Brors· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

E. Schruf

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Author profile →

3 papers

Recent·Most cited

High-resolution epigenetic profiling identifies novel regulators of COPD in human lung fibroblasts

U. Schwartz, M. Llamazares Prada, S. T. Pohl, M. Richter, R. Tamas, M. Schuler, C. Keller, V. Mijosek, T. Muley, M. A. Schneider, K. Quast, J. Hey, C. P. Heussel, A. Warth, H. Winter, , R. Jurkowska

This study identifies novel epigenetic and transcriptomic regulators of COPD in human lung fibroblasts across disease stages.

bioRxiv · Mar 28, 2022 · PreprintCell Biology

A polycomb-independent role of EZH2 in TGFβ1-damaged epithelium triggers a fibrotic cascade with mesenchymal cells

H. Q. Le, M. A. Hill, I. Kollak, W. Skronska-Wasek, V. Schroeder, J. Wirth, E. Schruf, K. Quast, F. E. Herrmann, M. J. Thomas, J. P. Garnett

The paper shows that EZH2, independent of Polycomb, drives fibrosis in TGFβ1-damaged epithelium by forming a new transcriptional complex with POL2 and nuclear actin.

bioRxiv · Jul 29, 2020Cell Biology

Recapitulating idiopathic pulmonary fibrosis related alveolar epithelial dysfunction in an iPSC-derived air-liquid interface model

E. Schruf, V. Schroeder, H. Q. Le, T. Schoenberger, D. Raedel, E. L. Stewart, K. Fundel-Clemens, T. Bluhmki, S. Weigle, M. Schuler, M. J. Thomas, R. Heilker, M. J. Webster, M. Dass, M. Frick, , J. P. Garnett

This study develops an iPSC-derived air-liquid interface model to mimic IPF-related bronchiolization and shows IPF-RC stimulation alters ATII differentiation and transcriptome profiles.

bioRxiv · Nov 4, 2019Cell Biology