Author

K. R. Vinothkumar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 4 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:protein folding & dynamics· 3 Assay:structural biology· 3 Organism:bacteria (other)· 2 Research Focus:cell signaling & trafficking· 2 Assay:cryo-EM· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

R. Subramanian· 2 shared A. Casanal· 1 shared A. Kumari· 1 shared C. Indiveri· 1 shared C. K. Arya· 1 shared G. Chopra· 1 shared G. Ramanathan· 1 shared J. Fine· 1 shared

Activity by Year

2017-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersBiochemistry

R. Subramanian

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Author profile →

5 papers

Recent·Most cited

Molecular determinants of Neu5Ac binding to tripartite ATP independent periplasmic (TRAP) transporter

P. Goyal, K. Dhanabalan, M. Scalise, R. Friemann, C. Indiveri, R. C. Dobson, K. R. Vinothkumar, R. Subramanian

The paper reports the structures of SiaQM from Fusobacterium nucleatum with and without Neu5Ac, revealing interactions and transport mechanisms.

bioRxiv · Mar 29, 2024Biochemistry

Decoding the Mechanism of Specific RNA Targeting by Ribosomal Methytransferases

J. Singh, R. Raina, K. R. Vinothkumar, R. Anand

This study determines the structure of 30S-KsgA and identifies factors guiding its specificity, enabling strategies to reverse methylation-mediated antibiotic resistance.

bioRxiv · Sep 15, 2021 · PreprintBiochemistry

Breaking a Strong Amide Bond: Structure and Properties of Dimethylformamidase.

C. K. Arya, S. Yadav, J. Fine, A. Casanal, G. Chopra, G. Ramanathan, K. R. Vinothkumar, R. Subramanian

This paper describes the structure and properties of Dimethylformamidase (DMFase) from Paracoccus, revealing new protein folds and a unique mononuclear iron active site that enables its function in harsh conditions.

bioRxiv · Dec 17, 2019Biochemistry

Structural insights into filament recognition by cellular actin markers

A. Kumari, S. Kesarwani, M. G. Javoor, K. R. Vinothkumar, M. Sirajuddin

The paper presents cryo-EM structures of phalloidin, lifeAct, and utrophin bound to F-actin, revealing their binding mechanisms and informing marker selection for actin studies.

bioRxiv · Nov 18, 2019Cell Biology

Structure of the deactive state of mammalian respiratory complex I

J. N. Blaza, K. R. Vinothkumar, J. Hirst

This study determines the structure of the deactive state of Bos taurus complex I using cryo-EM, revealing structural changes associated with the transition from active to deactive states.

bioRxiv · Jul 19, 2017Biochemistry