Author

K. Scharov

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

B. Rotblat· 3 shared D. Picard· 3 shared G. Leprivier· 3 shared G. Reifenberger· 3 shared M. Remke· 3 shared A. Kahler· 2 shared K. Voeltzke· 2 shared L. Hauffe· 2 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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3 shared papersCancer Biology

B. Rotblat

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The EIF4EBP1 gene encoding 4EBP1 is transcriptionally upregulated by MYC and linked to shorter survival in medulloblastoma

L. Hruby, K. Scharov, A. Delaidelli, D. Picard, C. Dunham, O. Lewandowska, T. Reiff, M. Larcher, C. Pouponnot, P. H. Sorensen, B. Rotblat, G. Reifenberger, M. Remke, G. Leprivier

This study shows that EIF4EBP1 is upregulated by MYC in medulloblastoma and linked to poorer patient survival.

bioRxiv · Mar 6, 2024 · PreprintCancer Biology

4EBP1/2 support tumorigenicity and cell survival during energetic stress by translationally regulating fatty acid synthesis

T. Levy, K. Voeltzke, L. Hauffe, K. Alasad, M. Snaebjornsson, R. Marciano, K. Scharov, M. Planque, K. Vriens, S. Christen, C. M. Funk, C. Hassiepen, A. Kahler, B. Heider, D. Picard, , G. Leprivier

This study shows 4EBP1/2 promote cell survival under glucose starvation by repressing fatty acid synthesis and maintaining redox balance, supporting tumorigenicity in cancer cells.

bioRxiv · Sep 9, 2022 · PreprintCell Biology

EIF4EBP1 is transcriptionally upregulated by MYCN and associates with poor prognosis in neuroblastoma

K. Voeltzke, K. Scharov, C. Funk, A. Kahler, D. Picard, L. Hauffe, M. F. Orth, M. Remke, I. Esposito, T. Kirchner, A. Schramm, B. Rotblat, T. G. P. Gruenewald, G. Reifenberger, G. Leprivier

This study shows EIF4EBP1 is upregulated by MYCN and linked to poor prognosis in neuroblastoma, with high expression associated with reduced survival and unfavorable histology.

bioRxiv · Dec 8, 2021Cancer Biology